Operating Status Summer 2024:

On-site (The internship will be performed entirely at the lab)

Student Requirements:

Students must be solely U.S. citizens. (Dual citizens and permanent residents are not eligible.)

Mission

To preserve and protect the health and performance of U.S. military personnel through research and training that advance understanding of the effects of ionizing radiation. This mission includes education and training to maintain a pool of qualified radiation biologists; and basic and applied research to identify and perform early development of measures to prevent, assess and treat radiation injury. AFRRI research thrusts include medical countermeasures, diagnosis of injury (biodosimetry), low dose/low dose rate/late effects, internalized radionuclides, and combined injury.

About the Lab

The Armed Forces Radiobiology Research Institute (AFRRI), an institute of the Uniformed Services University of the Health Sciences, was established in 1960 as a joint agency of the Army, Navy, and Air Force. AFRRI’s leads in the effort to preserve the health and performance of U.S. military personnel and to protect humankind through research that advances understanding of the biological effects of ionizing radiation. To these ends, the institute collaborates with other government facilities, academic institutions, and civilian laboratories in the United States and other countries. In addition, it provides medical training and emergency response to manage incidents related to radiation exposure. AFRRI is located on the grounds of the Naval Support Activity Bethesda, which is also home to the Walter Reed National Military Medical Center.

What is unique about this lab?

AFRRI is the only DoD radiobiology research institute. AFFRI is also unique with having multiple types of ionizing radiation sources under one roof to include gamma rays, alpha particles, and mixed field sources. The unique resources of AFRRI enable its advancements in the protection of soldiers and citizens.

About the Internship

At AFRRI, there are 5 major research areas that encompasses the prevention, assessment, and treatment of injuries resulting from the effects of ionizing radiation. In order to meet these objects our research focuses on Biological Dosimetry, Radiation Combined Injury, Internal Contamination/Toxic Metals, Space Radiation and Radiation Countermeasures. Our PIs take on students in high school all the way to graduate school. There is no set of prerequisite skills that are required to intern with us. We will meet you where your skills are and build off of them during your internship. However, it is helpful to know how to conduct serial dilutions, perform research using aseptic technique, operate a centrifuge, culture cells, and perform Western Blots, ELISA, and Luminex assays. If you do not know how to do those, then that is your starting point and we will work from there. The level of responsibility the intern would have depends on prior experience working in a lab. If the student shows competence in conducting assays and interpreting data, they may be given a segment of a project to complete. If a student requires more supervision, they will assist other laboratory staff in conducting experiments.

What will I do any given day as an intern at this lab?

Interns participate in lab functions in a number of ways including (but not limited to) assisting mentors with guided research projects; attending seminars, conferences and a "Medical Effects of Ionized Radiation" course; networking with STEM professionals and other interns; touring labs and radiation sources; and other professional development activities.

What majors and disciplines are a good fit for interning at this lab?

The primary fields of interest are:

• Biology
• Chemistry
• Physics
• Radiobiology

What kinds of projects do interns at this lab participate in?

The following are examples of projects to which interns may be assigned:

Biological Dosimetry: The goal of the Biological Dosimetry program is to develop rapid, high-precision analytical methods that assess radiation exposure doses from clinical samples and thus aid in the triage and medical management of radiological casualties for military personnel and civilian responders.

Radiation Injury Research: The Radiation Injury program is tasked with developing a comprehensive understanding of the biology of radiation injury combined with traumatic wounds, burns, hemorrhaging, or infections and investigate treatment strategies including biological response modifiers, new antimicrobial agents, probiotics, and stem cells, used individually or in combination.

Internal Contamination and Toxic Metals Research: Research on the chemical and radiological toxicity of embedded fragments is applicable to a variety of battlefield scenarios as well as terrorism events.

Medical Countermeasures: The Medical Countermeasures program identifies and tests candidates that have the potential to be radioprotectors, radiomitigators, radiotherapeutics, for treatment of Acute Radiation Syndrome, to include seeking FDA approval following the Animal Rule.